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Mafatm1Eyc
Targeted Allele Detail
Summary
Symbol: Mafatm1Eyc
Name: MAF bZIP transcription factor A; targeted mutation 1, Alain Eychene
MGI ID: MGI:4868450
Synonyms: mafAflox
Gene: Mafa  Location: Chr15:75617339-75620077 bp, - strand  Genetic Position: Chr15, 34.82 cM
Alliance: Mafatm1Eyc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:164344
Parent Cell Line:  CK35 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA FRT-flanked PGK-neo selection cassette resides downstream of the polyadenylation signal of the endogenous gene, and loxP sites are present 46 bp upstream of the ATG translation initiation codon and downstream of the neo cassette. The 3' loxP site is followed by the coding sequence for E. coli beta-galactosidase (lacZ) with a nuclear localization signal. (J:164344)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mafa Mutation:  20 strains or lines available
References
Original:  J:164344 Lecoin L, et al., MafA transcription factor identifies the early ret-expressing sensory neurons. Dev Neurobiol. 2010 Jun;70(7):485-97
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory