Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(S100b-EGFP/cre/ERT2)22Amc
Name:	transgene insertion 22, Andrew P McMahon
MGI ID:	MGI:4849988
Synonyms:	S100b-GCE
Transgene:	Tg(S100b-EGFP/cre/ERT2)22Amc  Location: unknown
Alliance:	Tg(S100b-EGFP/cre/ERT2)22Amc page

Strain of Origin:

(C57BL/6 x DBA)F1

Transgene Type:    Transgenic (Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Tg(S100b-EGFP/cre/ERT2)22Amc expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse S100b (MGI:98217)   Mutation details: A targeting construct containing the eGFPCreERT2 (GCE) cassette and FRT site flanked Kanamycin/neomycin selection cassette was inserted into the consensus start ATG codon of the gene in a BAC (RP23-213P2). The PGK-Neo/Kan cassette was removed by transient Flpe-recombinase expression. The resulting BAC transgene was microinjected into (C57BL/6 x DBA)F1 donor eggs. Founder line 22 was subsequently established. GFP fluorescence is not detectable by fluorescent microscope examination of whole embryos, bones or neural tube sagittal slices from embryos aged 15.5dpc. Tamoxifen induced cre recombinase activity is detected in a subset of the GFP immunoreactive-positive cells in bone. (J:159099)

Activity:	Tissue activity of this recombinase allele
Driver:	S100b (mouse) Summary of all recombinase alleles driven by S100b. Comparative matrix view of recombinase activities Alliance mouse S100b gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:159099 McMahon A, et al., Summary of mouse strains characterized by GUDMAP consortium. Unpublished. 2010;
All:	1 reference(s)