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Slc8a1m51207Hubr
Chemically induced Allele Detail
Summary
Symbol: Slc8a1m51207Hubr
Name: solute carrier family 8 (sodium/calcium exchanger), member 1; mutation 51207, Hubrecht Institute
MGI ID: MGI:4849923
Synonyms: 5120-7, HI-07, Ncx1N874K, Slc8a1m1Hubr
Gene: Slc8a1  Location: Chr17:81680534-82045806 bp, - strand  Genetic Position: Chr17, 51.29 cM
Alliance: Slc8a1m51207Hubr page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis results in a T to A transversion in exon 9 that results in the amino acid substitution of lysine for asparagine at position 874 (N874K). (J:167034)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 13 assay results
In Structures Affected by this Mutation: 9 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc8a1 Mutation:  55 strains or lines available
References
Original:  J:167034 Wansleeben C, et al., A novel mutant allele of Ncx1: a single amino acid substitution leads to cardiac dysfunction. Int J Dev Biol. 2010;54(10):1465-71
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory