Tg(PSEN1)R8-1Dbo
Transgene Detail
|
|
| Symbol: |
Tg(PSEN1)R8-1Dbo |
| Name: |
transgene insertion R8-1, David R Borchelt |
| MGI ID: |
MGI:4849832 |
| Synonyms: |
R8-1 |
| Transgene: |
Tg(PSEN1)R8-1Dbo Location: unknown
|
| Alliance: |
Tg(PSEN1)R8-1Dbo page
|
|
| Strain of Origin: |
Not Specified
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(PSEN1)R8-1Dbo expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
PSEN1 (5663) |
|
|
|
| |
|
Mutation details: The transgene consists of a mouse prion promoter and a cDNA encoding wild-type human presenilin 1. Transgene expression was verified by Northern and Western blot analysis of brain extracts derived from transgenic animals. Lines S8-4, R8-1, H8-4, and B8-1 were generated.
(J:34323)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:34323 Thinakaran G, et al., Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron. 1996 Jul;17(1):181-90 |
| All: |
3 reference(s) |
|
Analysis Tools
