Tg(CAG-flpe)#Ito
Transgene Detail
|
|
| Symbol: |
Tg(CAG-flpe)#Ito |
| Name: |
transgene insertion, Shigeyoshi Itohara |
| MGI ID: |
MGI:4845873 |
| Synonyms: |
CAG-FLPe |
| Transgene: |
Tg(CAG-flpe)#Ito Location: unknown
|
| Alliance: |
Tg(CAG-flpe)#Ito page
|
|
|
|
| Transgene Type: |
|
Transgenic (Recombinase) |
| Mutation: |
|
Insertion
|
| |
|
Tg(CAG-flpe)#Ito expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| chicken |
CAG |
|
|
| |
|
Mutation details: The CAG promoter (chicken beta-actin promoter with CMV enhancers) was used to drive expression of a FLPe gene with a nuclear localization signal. Five founder lines were established (lines 16, 32, 36, 37 and 41) with lines 16, 32 and 36 exhibiting 100% recombination when crossed to a mouse containing an frt-flanked allele; 10/11 mice of line 37 showed recombination. Mosaicism was noted in 2/9 of line 16 and in 1/8 of line 32 double transgenic mice. # is used when no line is specified.
(J:108559)
|
|
|
|
Activity: |
 Tissue activity of this recombinase allele
|
|
Driver:
|
CAG
(chicken)
|
| |
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:166397 Fujii T, et al., Essential role of p400/mDomino chromatin-remodeling ATPase in bone marrow hematopoiesis and cell-cycle progression. J Biol Chem. 2010 Sep 24;285(39):30214-23 |
| All: |
48 reference(s) |
|
Analysis Tools
