Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(GFAP-Ccl2)JE95Rmra
Name:	transgene insertion JE95, Richard Ransohoff
MGI ID:	MGI:4843357
Synonyms:	huGFAP-CCL2hi tg+, huGFAP-MCP-1hi tg, huGFAP-MCP-1 tg+, JE95, JE-95
Transgene:	Tg(GFAP-Ccl2)JE95Rmra  Location: unknown
Alliance:	Tg(GFAP-Ccl2)JE95Rmra page

Strain of Origin:

(SWR/J x SJL/J)F1

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(GFAP-Ccl2)JE95Rmra expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Ccl2 (MGI:98259)   Mutation details: The huGFAP-MCP-1 transgene was designed with the 2.2 kb promoter region from the human GFAP gene upstream of a mouse 1.7 kb mouse Ccl2 genomic DNA sequence. Line JE95 exhibited the highest expression level. (J:133880)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:133880 Huang D, et al., Pertussis toxin-induced reversible encephalopathy dependent on monocyte chemoattractant protein-1 overexpression in mice. J Neurosci. 2002 Dec 15;22(24):10633-42
All:	3 reference(s)