Kcnv2tm1(KOMP)Wtsi
Targeted Allele Detail
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| Symbol: |
Kcnv2tm1(KOMP)Wtsi |
| Name: |
potassium channel, subfamily V, member 2; targeted mutation 1, Wellcome Trust Sanger Institute |
| MGI ID: |
MGI:4840969 |
| Synonyms: |
Kcnv2tm1, Kcnv2tm1a(KOMP)Wtsi |
| Gene: |
Kcnv2 Location: Chr19:27299988-27314579 bp, + strand Genetic Position: Chr19, 21.88 cM
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| Alliance: |
Kcnv2tm1(KOMP)Wtsi page
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| IMPC: |
Kcnv2 gene page |
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| Mutant Cell Lines: |
EPD0452_1_E05, EPD0600_3_B03, EPD0600_3_B09, EPD0600_3_B10, EPD0600_3_C08, EPD0600_3_D08, EPD0600_3_F04, EPD0600_3_F06, EPD0600_3_G01, EPD0600_3_H02, EPD0600_3_H04, EPD0600_3_H09 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:82809
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| Parent Cell Line: |
JM8A3.N1 (ES Cell)
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| Strain of Origin: |
C57BL/6N-Atm1Brd
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| Project Collection: |
KOMP-CSD
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| Allele Type: |
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Targeted (Conditional ready, Null/knockout, Reporter) |
| Mutation: |
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Insertion
Vector: L1L2_Del_BactPneo_FFL
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Mutation details: The L1L2_Del_BactPneo_FFL cassette was inserted at position 27299497 of Chromosome 19 upstream of exon 1 (Build GRCm39). The cassette is composed of an FRT site followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a loxP site. A second loxP site is inserted downstream of exon 1 at position 27398917. Exon 1 is thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. Further information on targeting strategies used for this and other KOMP alleles can be found at http://www.knockoutmouse.org/about/targeting-strategies.
(J:148605)
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| Original: |
J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009; |
| All: |
4 reference(s) |
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Analysis Tools
