Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sufutm1Hui
Name:	SUFU negative regulator of hedgehog signaling; targeted mutation 1, Chi-chung Hui
MGI ID:	MGI:4840420
Synonyms:	Sufufl, Sufuflox, SuFuloxP
Gene:	Sufu  Location: Chr19:46385335-46477243 bp, + strand  Genetic Position: Chr19, 38.85 cM
Alliance:	Sufutm1Hui page

Germline Transmission:	Earliest citation of germline transmission: J:166285
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     Exons 4-8 were surrounded by loxP sites. A neomycin selection cassette was inserted as well. (J:166285)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	79 assay results 5 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sufu Mutation:	59 strains or lines available

Original:	J:166285 Pospisilik JA, et al., Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. Cell. 2010 Jan 8;140(1):148-60
All:	24 reference(s)