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Tg(Gata4*G4-lacZ)1Blk
Transgene Detail
Summary
Symbol: Tg(Gata4*G4-lacZ)1Blk
Name: transgene insertion 1, Brian L Black
MGI ID: MGI:4840266
Synonyms: Gata4-G4-lacZ
Transgene: Tg(Gata4*G4-lacZ)1Blk  Location: unknown  
Alliance: Tg(Gata4*G4-lacZ)1Blk page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe 1107 bp intronic G4 endodermal enhancer sequence (GenBank Acc ID HM212783) was cloned in front of an Hsp68-lacZ reporter sequence in a reporter plasmid. The construct was digested from the plasmid backbone, purified, and used for pronuclear injection. Seven founders were generated. Six showed consisted lacZ expression patterns during embryonic development. (J:165741)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:165741 Rojas A, et al., Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer. Dev Biol. 2010 Oct 15;346(2):346-55
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory