Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Gata4*G4-cre)1Blk
Name:	transgene insertion 1, Brian L Black
MGI ID:	MGI:4840244
Synonyms:	G4Gp-creTg, Gata4-G4Gp-creTg
Transgene:	Tg(Gata4*G4-cre)1Blk  Location: unknown
Alliance:	Tg(Gata4*G4-cre)1Blk page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Gata4*G4-cre)1Blk expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Gata4 (MGI:95664)   Mutation details: The G4 intronic enhancer (1107 bp, GenBank Acc ID HM212783) of the mouse Gata4 gene was fused to the Gata4 minimal promoter (-443 to +52 of Gata4 sequence) and was cloned into a cre expression plasmid containing cre cDNA and SV40 splice and polyA sites. The construct was purified for pronuclear injection. Male founders were crossed to FVB females. Line numbers were not specified in the original reference. (J:165741)

Activity:	Tissue activity of this recombinase allele
Driver:	Gata4 (mouse) Summary of all recombinase alleles driven by Gata4. Alliance mouse Gata4 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:165741 Rojas A, et al., Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer. Dev Biol. 2010 Oct 15;346(2):346-55
All:	2 reference(s)