Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fgf8tm1(cre)Itl
Name:	fibroblast growth factor 8; targeted mutation 1, inGenious Targeting Laboratory
MGI ID:	MGI:4839641
Synonyms:	Fgf8-IRES-Cre, Fgf8tm1(cre)Igl
Gene:	Fgf8  Location: Chr19:45725237-45731354 bp, - strand  Genetic Position: Chr19, 38.75 cM, cytoband C3-D
Alliance:	Fgf8tm1(cre)Itl page

Germline Transmission:	Earliest citation of germline transmission: J:165806
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Fgf8tm1(cre)Itl expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Fgf8 (MGI:99604)   Mutation details: An IRES-cre cassette was inserted immediately downstream of the coding sequence at the 3' end of the Fgf8 locus. (J:165806)

Activity:	Tissue activity of this recombinase allele
Driver:	Fgf8 (mouse) Summary of all recombinase alleles driven by Fgf8. Alliance mouse Fgf8 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

8 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgf8 Mutation:	18 strains or lines available

Original:	J:165806 Toyoda R, et al., FGF8 acts as a classic diffusible morphogen to pattern the neocortex. Development. 2010 Oct;137(20):3439-48
All:	6 reference(s)