Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Cela1-Spink3)#Rali
Name:	transgene insertion, Rodger A Liddle
MGI ID:	MGI:4838201
Synonyms:	Tg(Psti-1)
Transgene:	Tg(Cela1-Spink3)#Rali  Location: unknown
Alliance:	Tg(Cela1-Spink3)#Rali page

Strain of Origin:

B6SJLF1

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Mutation details: The 510 bp rat elastase 1 enhancer/promoter (Cela1) was used to drive expression of a rat pancreatic secretory trypsin inhibitor minigene (Spink3) containing all four exons and 2 kb of 3' flanking DNA. The three entrons were all shortened for ease in handling. Two of the four founders identified were used to extablish lines of transgenic mice. (J:96743)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:96743 Nathan JD, et al., Transgenic expression of pancreatic secretory trypsin inhibitor-I ameliorates secretagogue-induced pancreatitis in mice. Gastroenterology. 2005 Mar;128(3):717-27
All:	2 reference(s)