Pak2 Western blot Gene Expression Assay - GXD

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Gene Expression Data
Assay Details

Assay

Reference:	J:157948 Jiang XS, et al., Activation of Rho GTPases in Smith-Lemli-Opitz syndrome: pathophysiological and clinical implications. Hum Mol Genet. 2010 Apr 1;19(7):1347-57
Assay type:	Western blot
MGI Accession ID:	MGI:4836892
Gene symbol:	Pak2
Gene name:	p21 (RAC1) activated kinase 2

Antibody:	Anti-Phospho-Pak1 (Thr423)/Pak2 (Thr402)
Detection system:	Secondary antibody coupled to alkaline phosphatase
Assay notes:	The antibody used in this assay recognizes the phosphorylated forms of both Pak1 and Pak2; both genes have been annotated.

Results

Image: S4C P-Pak 1/2

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Genetic Background	Mutant Allele(s)	Sex
Sc5d +/+	E18.5	TS26: brain	Present	involves: 129S1/Sv * 129X1/SvJ		Not Specified
Sc5d -/-	E18.5	TS26: brain	Strong (a)	involves: 129S1/Sv * 129X1/SvJ	Sc5d^tm1Fdp/Sc5d^tm1Fdp	Not Specified

Notes:
(a) Expression level of the phosphorylated protein was significantly increased in the mutant compared with control brain tissue.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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