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Gene Expression Data
Assay Details
Assay
Reference: J:157948 Jiang XS, et al., Activation of Rho GTPases in Smith-Lemli-Opitz syndrome: pathophysiological and clinical implications. Hum Mol Genet. 2010 Apr 1;19(7):1347-57
Assay type: Western blot
MGI Accession ID: MGI:4836612
Gene symbol: Cfl1
Gene name: cofilin 1, non-muscle
Antibody: Anti-Phospho-Cofilin-1 (Ser3)
Detection system: Secondary antibody coupled to alkaline phosphatase
Results Image: 1C P-Cofilin-1
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex Note
Dhcr7 +/+ E18.5 TS26: brain Present involves: 129S4/SvJae Not Specified 7 pooled embryos.
Dhcr7 delta/delta E18.5 TS26: brain Strong (a) involves: 129S4/SvJae Dhcr7tm1Fdp/Dhcr7tm1FdpNot Specified 7 pooled embryos.
Notes:
(a) Expression level of the phosphorylated protein was significantly increased in the mutant compared with control brain tissue.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory