Tg(Ins2-BCL2L1)1Dh
Transgene Detail
|
|
| Symbol: |
Tg(Ins2-BCL2L1)1Dh |
| Name: |
transgene insertion 1, Douglas Hanahan |
| MGI ID: |
MGI:4836173 |
| Transgene: |
Tg(Ins2-BCL2L1)1Dh Location: unknown
|
| Alliance: |
Tg(Ins2-BCL2L1)1Dh page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(Ins2-BCL2L1)1Dh expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
BCL2L1 (598) |
|
|
|
| |
|
Tg(Ins2-BCL2L1)1Dh expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| rat |
Ins2 (24506) |
|
|
|
| |
|
Mutation details: A0.8 kb fragment of human BCL2L1 was placed under the control of a 9.5 kb 5' regulatory region of the rat insulin II gene. Two independent founder lines were obtained, both with expression levels 20 fold greater thean the endogenous gene. Line 1 was used in further crosses.
(J:76998)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:76998 Naik P, et al., The rise and fall of apoptosis during multistage tumorigenesis: down-modulation contributes to tumor progression from angiogenic progenitors. Genes Dev. 1996 Sep 1;10(17):2105-16 |
| All: |
1 reference(s) |
|
Analysis Tools
