Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Msx2-cre/ERT)27Alj
Name:	transgene insertion 27, Alexandra L Joyner
MGI ID:	MGI:4834769
Synonyms:	Msx2-CreERT
Transgene:	Tg(Msx2-cre/ERT)27Alj  Location: unknown
Alliance:	Tg(Msx2-cre/ERT)27Alj page

Strain of Origin:

Swiss Webster

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Msx2-cre/ERT)27Alj expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Msx2   Mutation details: A transgenic construct was generated that contained cre/ERT, beta-globin intron, LacZtag, and SV40polyA coding sequences under control of an apical ectodermal ridge (AER)-specific 520 bp Msx2 promoter. The purified construct was injected into Swiss Webster zygotes. Nine founders were generated with eight transmitting the transgene. Four expressed cre/ERT in the apical ectodermal ridge (AER). Studies were performed using one line (no. 27) that showed the strongest expression. (J:62572)

Activity:	Tissue activity of this recombinase allele
Driver:	Msx2 (species not specified) Summary of all recombinase alleles driven by Msx2. Comparative matrix view of recombinase activities

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:62572 Kimmel RA, et al., Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation. Genes Dev. 2000 Jun 1;14(11):1377-89
All:	1 reference(s)