About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:163582 Paul E, et al., Widespread expression of the Supv3L1 mitochondrial RNA helicase in the mouse. Transgenic Res. 2010 Aug;19(4):691-701
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:4833961
Gene symbol: Supv3l1
Gene name: suppressor of var1, 3-like 1 (S. cerevisiae)
Reporter: GFP
Direct Detection
Results
Specimen 3A': embryonic day 0.5; Supv3l1tm6Jkl/Supv3l1+ (more )
Note: One-cell embryos. Embryos derived from matings of Supv3L1tm6Jkl/+ males and wild type females (paternal transmission of the reporter allele).
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Absent 3A' Embryos derived from matings of Supv3L1tm6Jkl/+ males and wild type females (paternal transmission of the reporter allele).

Specimen 3B': embryonic day 1.5; Supv3l1tm6Jkl/Supv3l1+ (more )
Note: Two-cell embryos. Embryos derived from matings of Supv3L1tm6Jkl/+ males and wild type females (paternal transmission of the reporter allele).
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Absent 3B' Embryos derived from matings of Supv3L1tm6Jkl/+ males and wild type females (paternal transmission of the reporter allele).

Specimen 3C': embryonic day 3.5; Supv3l1tm6Jkl/Supv3l1+ (more )
Note: Blastocysts. Embryos derived from matings of Supv3L1tm6Jkl/+ males and wild type females (paternal transmission of the reporter allele).
Structure Level Pattern Image Note
TS5: inner cell mass Weak 3C' Embryos derived from matings of Supv3L1tm6Jkl/+ males and wild type females (paternal transmission of the reporter allele). Approximately 50% of blastocysts were found to display EGFP fluorescence above background.
TS5: trophectoderm Weak 3C' Embryos derived from matings of Supv3L1tm6Jkl/+ males and wild type females (paternal transmission of the reporter allele). Approximately 50% of blastocysts were found to display EGFP fluorescence above background.

Specimen 3D': embryonic day 0.5; Supv3l1tm6Jkl/Supv3l1+ (more )
Note: One-cell embryos. Embryos obtained from Supv3L1tm6Jkl/+ females mated with wild-type males (maternally transmitted reporter).
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Strong 3D' Embryos obtained from Supv3L1tm6Jkl/+ females mated with wild-type males (maternally transmitted reporter).

Specimen 3E': embryonic day 1.5; Supv3l1tm6Jkl/Supv3l1+ (more )
Note: Two-cell embryos. Embryos obtained from Supv3L1tm6Jkl/+ females mated with wild-type males (maternally transmitted reporter).
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Strong 3E' Embryos obtained from Supv3L1tm6Jkl/+ females mated with wild-type males (maternally transmitted reporter).

Specimen 3F': embryonic day 3.5; Supv3l1tm6Jkl/Supv3l1+ (more )
Note: Blastocysts. Embryos obtained from Supv3L1tm6Jkl/+ females mated with wild-type males (maternally transmitted reporter).
Structure Level Pattern Image Note
TS5: inner cell mass Weak 3F' Embryos obtained from Supv3L1tm6Jkl/+ females mated with wild-type males (maternally transmitted reporter). At this stage, approximately half of the embryos were positive for EGFP.
TS5: trophectoderm Weak 3F' Embryos obtained from Supv3L1tm6Jkl/+ females mated with wild-type males (maternally transmitted reporter). At this stage, approximately half of the embryos were positive for EGFP.

Specimen 4B,C: embryonic day 7.5; Supv3l1tm6Jkl/Supv3l1+ (more )
Note: Late primitive streak stage.
Structure Level Pattern Image Note
TS11: embryo Strong 4B , 4C Expression is in all three cell layers.
TS11: yolk sac Strong 4B , 4C Expression is in all three cell layers.

Specimen Maternal tissue: postnatal; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: endometrium Absent

Specimen 4D: embryonic day 9.5; Supv3l1tm6Jkl/Supv3l1+ (more )
Note: 21-29 somites.
Structure Level Pattern Image Note
TS15: embryo Present Widespread 4D

Specimen 4E: embryonic day 11.5; Supv3l1tm6Jkl/Supv3l1+ (more )
Note: 43-48 somites.
Structure Level Pattern Image Note
TS19: embryo Present Widespread 4E

Specimen 4F: embryonic day 13.5; Supv3l1tm6Jkl/Supv3l1+ (more )
Note: 60 somites.
Structure Level Pattern Image Note
TS21: embryo Present Widespread 4F
TS21: liver Weak 4F

Specimen 4G: embryonic day 16.5; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS24: embryo Present Widespread 4G

Specimen 4H: postnatal newborn; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS27: mouse Present Widespread 4H

Specimen 4I: embryonic day 16.5; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS24: yolk sac Present 4I

Specimen Not shown, E16.5: embryonic day 16.5; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS24: amnion Present

Specimen Not shown, P5: postnatal day 5; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: mouse Present Widespread
TS28: brain Strong
TS28: eye Strong
TS28: heart Strong
TS28: skeletal muscle Strong
TS28: skin Strong
TS28: liver Weak

Specimen 5A thymus: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: thymus Strong 5A thymus +/-

Specimen 5A brain: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: brain Strong 5A brain +/-

Specimen 5A pancreas: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: pancreas Present 5A pancreas +/-

Specimen 5A eyes: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: eye Strong 5A eyes +/-

Specimen 5A testes: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: testis Very strong 5A testes +/-

Specimen 5A skeletal muscle: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: skeletal muscle Present 5A Skeletal muscle +/-

Specimen 5A heart: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: heart Present 5A heart +/-

Specimen 5A ears: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: ear Present 5A ears +/-

Specimen 5A kidney: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: metanephros Present 5A kidney

Specimen 5A liver: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: liver Weak 5A liver

Specimen 5A lung: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: lung Weak 5A lung

Specimen 5A spleen: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: spleen Present 5A spleen

Specimen Not shown, skin: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: skin Weak

Specimen Not shown, brain: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: amygdala Strong
TS28: hippocampus Strong
TS28: hypothalamus Strong
TS28: thalamus Strong
TS28: neocortex Present

Specimen 5B targeted testis: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: testis Present 5B targeted testes

Specimen 5B targeted eyes: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: eye Present 5B targeted eyes

Specimen 5B targeted ears: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: ear Present 5B targeted ears

Specimen 5B targeted muscle: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: musculature Present 5B targeted muscle

Specimen 5B targeted sem. ves.: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: seminal vesicle Present 5B targeted seminal vesicles

Specimen 5B targeted kidney: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: metanephros Present 5B targeted kidney

Specimen 5B targeted spleen: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: spleen Present 5B targeted spleen

Specimen 5B targeted pancreas: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: pancreas Present 5B targeted pancreas

Specimen 6B: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: dermis Present 6B Expression is in all layers.
TS28: epidermis Present 6B Expression is in all layers.

Specimen 6E,F: postnatal week 10; Supv3l1tm6Jkl/Supv3l1+ (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer inner segment Present 6E , 6F
TS28: retina outer plexiform layer Present 6E , 6F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory