Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Gad1tm2(cre)Mony
Name:	glutamate decarboxylase 1; targeted mutation 2, Hannah Monyer
MGI ID:	MGI:4830465
Synonyms:	GAD-Cre
Gene:	Gad1  Location: Chr2:70391644-70432358 bp, + strand  Genetic Position: Chr2, 41.63 cM, cytoband D
Alliance:	Gad1tm2(cre)Mony page

Germline Transmission:	Earliest citation of germline transmission: J:134013
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Gad1tm2(cre)Mony expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Gad1 (MGI:95632)   Mutation details: A cassette containing cre recombinase was inserted 30 bp upstream of the translation initiation codon of Gad1 in ES cells by homologouse recombination. (J:134013)

Activity:	Tissue activity of this recombinase allele
Driver:	Gad1 (mouse) Summary of all recombinase alleles driven by Gad1. Alliance mouse Gad1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gad1 Mutation:	64 strains or lines available

Original:	J:134013 Fuchs EC, et al., Genetically altered AMPA-type glutamate receptor kinetics in interneurons disrupt long-range synchrony of gamma oscillation. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3571-6
All:	12 reference(s)