Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Akr1b7-RFP)9Amc
Name:	transgene insertion 9, Andrew P McMahon
MGI ID:	MGI:4830367
Synonyms:	Akr1b7TagRFP-T, Akr1b7-TagRFP-T
Transgene:	Tg(Akr1b7-RFP)9Amc  Location: unknown
Alliance:	Tg(Akr1b7-RFP)9Amc page

Strain of Origin:

(C57BL/6 x DBA/2)F1

Transgene Type:    Transgenic (Reporter) Mutation:    Insertion   Mutation details: A mouse bacterial artificial chromosome (BAC) containing the entire mouse Akrib7 gene, was modified by inserting the TagRFP-T reporter sequence. Express of the Red Fluorescent Protein (TagRFP-T variant) is under the direction of the mouse Akrib7, aldo-keto reductase family 1, member B7, promoter. Transgene expression is detected at high levels in the adrenal glands and endothelial cells of renal medullary arterioles of transgenic embryos aged E15.5. Renal vasculature associated expression is observed in Smooth Muscle Actin immunohistochemical positive cells that are closely associated with FLK1 and PECAM positive intrarenal arteries. Other possible sites of expression have not been characterized. (J:159099)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:163980 McMahon AP, DDS 2010-09-22-8OkdUc. MGI Direct Data Submission. 2010;
All:	2 reference(s)