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Recktm1.1Noda
Targeted Allele Detail
Summary
Symbol: Recktm1.1Noda
Name: reversion-inducing-cysteine-rich protein with kazal motifs; targeted mutation 1.1, Makoto Noda
MGI ID: MGI:4830337
Synonyms: Reckfl, Reckflex2, ReckL, ReckLow, Rlow
Gene: Reck  Location: Chr4:43875530-43944806 bp, + strand  Genetic Position: Chr4, 23.05 cM
Alliance: Recktm1.1Noda page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:163845
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 2 was floxed. The FRT flanked neo cassette used for ES cell selection was removed by flp mediated recombination. (J:163845)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 11 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Reck Mutation:  46 strains or lines available
References
Original:  J:163845 Chandana EP, et al., Involvement of the Reck tumor suppressor protein in maternal and embryonic vascular remodeling in mice. BMC Dev Biol. 2010;10:84
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory