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Gene Expression Data
Assay Details
Assay
Reference: J:35370 Rantakokko J, et al., Mouse cathepsin K: cDNA cloning and predominant expression of the gene in osteoclasts, and in some hypertrophying chondrocytes during mouse development. FEBS Lett. 1996 Sep 16;393(2-3):307-13
Assay type: RNA in situ
MGI Accession ID: MGI:4830252
Gene symbol: Ctsk
Gene name: cathepsin K
Probe: pMCatK-7
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Specimens were decalcified in 5% EDTA for 2 days.
Results
Specimen 4A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: metatarsus Present Regionally restricted 4A Expression is in central parts of the primary ossification center.
Specimen 4B,C: embryonic day 18.5 (more )
Note: (C) is a magnification of the boxed area in (B).
Structure Level Pattern Image Note
TS26: metatarsus Present 4C , 4B
Specimen 4D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: femur Present Regionally restricted 4D Expression is on trabecular bone surfaces and in calcifying growth cartilage.
Specimen 4E: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: femur Present Regionally restricted 4E Expression is on endosteal and trabecular bone surfaces.
Specimen 5D: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: epiphyseal plate Present Regionally restricted 5D Expression is in some chondrocytes which had recently undergone mitosis.
Specimen 5E: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: epiphyseal plate Present Regionally restricted 5E Expression is in some hypertrophic chondrocytes close to the osteochondral junction. With extended exposure, signals were also detected over individual hypertrophying chondrocytes in central regions of the epiphyseal heads.
Specimen Not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: limb Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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