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Gene Expression Data
Assay Details
Assay
Reference: J:10348 Kadomatsu K, et al., A retinoic acid responsive gene MK found in the teratocarcinoma system is expressed in spatially and temporally controlled manner during mouse embryogenesis. J Cell Biol. 1990 Mar;110(3):607-16
Assay type: RNA in situ
MGI Accession ID: MGI:4821438
Gene symbol: Mdk
Gene name: midkine
Probe: Mdk cDNA1
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 1b: embryonic day 5.5 (more )
Structure Level Pattern Image Note
TS8: embryo Absent 1b

Specimen 1e: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Present Uniform 1e
TS11: ectoplacental cone Absent 1e
TS28: decidua Absent 1e

Specimen 1h: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Present Uniform 1h
TS15: future brain Present 1h
TS15: gut Present 1h
TS15: otocyst Present 1h
TS15: somite Present 1h

Specimen 1o: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Present 1o
TS11: ectoplacental cone Absent 1o

Specimen 2b: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: embryo Present Regionally restricted 2b Expression was detected at some level over the entire embryo.
TS19: brain Present Regionally restricted 2b Expression is in the brain ectoderm around the lens and brain ventricles.
TS19: future adenohypophysis Present 2b
TS19: jaw primordium Present 2b
TS19: limb Present 2b
TS19: lung Present 2b
TS19: metanephros Present 2b
TS19: pancreas primordium Present 2b
TS19: stomach Present 2b
TS19: sclerotome Present Regionally restricted 2b Expression is in the caudal half.
TS19: intestine Present Regionally restricted 2b Expression is in the small intestine.

Specimen 2d: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: brain Present Regionally restricted 2d Expression is in the brain ectoderm around the lens and brain ventricles.
TS21: adenohypophysis Present 2d
TS21: limb Present 2d
TS21: lower jaw Present 2d
TS21: lung Present 2d
TS21: metanephros Present 2d
TS21: pancreas Present 2d
TS21: stomach Present 2d
TS21: upper jaw Present 2d
TS21: intestine Present Regionally restricted 2d Expression is in the small intestine.
TS21: tail sclerotome Present Regionally restricted 2d Expression is in the caudal half.

Specimen 3d: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: pancreas primordium Present Patchy 3d Expression corresponds to the endodermal epithelium.

Specimen 3f: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pancreas Present Patchy 3f Expression corresponds to the endodermal epithelium.
TS21: intestine epithelium Very strong 3f
TS21: intestine mesenchyme Absent 3f

Specimen 3h: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lung epithelium Very strong 3h
TS19: lung mesenchyme Weak 3h

Specimen 3j: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung epithelium Very strong 3j
TS21: lung mesenchyme Present 3j

Specimen 4d: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Very strong 4d

Specimen 4e: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: adenohypophysis Very strong 4e

Specimen 4f: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: retina Very strong 4f
TS19: eye Weak 4f

Specimen 4j: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cornea Very strong 4j
TS21: retina Very strong 4j
TS21: lens Weak 4j

Specimen 4k: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: brain Present Regionally restricted 4k Expression is in the brain ectoderm around the ventricles.

Specimen 4l: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: brain Present Regionally restricted 4l Expression is in the brain ectoderm around the ventricles.

Specimen 5d: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: sclerotome Very strong Regionally restricted 5d Expression is in the caudal half.

Specimen 5e: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: jaw primordium Present Uniform 5e Upper and lower jaw.

Specimen 5f: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: limb Present Uniform 5f Expression in the center of pre-cartilage was slightly less compared to the rest of the limb.

Specimen 6d: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present 6d
TS19: ureteric bud Present 6d

Specimen 6e: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: metanephros Present Patchy 6e

Specimen 6f: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vertebral cartilage condensation Present Regionally restricted 6f Expression is in the peripheral region of each vertebral body.
TS21: metanephros Present Patchy 6f Expression is in epithelial cells.

Specimen 6h: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: metanephros Present Patchy 6h

Specimen 6j: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: metanephros Present 6j

Specimen 6l: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: metanephros Present 6l


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory