Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(ACTB-UPF1*R844C)581Hcd
Name:	transgene insertion 581, Harry C Dietz
MGI ID:	MGI:4820740
Synonyms:	RNT1 Dom Neg
Transgene:	Tg(ACTB-UPF1*R844C)581Hcd  Location: unknown
Alliance:	Tg(ACTB-UPF1*R844C)581Hcd page

Strain of Origin:

(C57BL/6 x 129)F1

Transgene Type:    Transgenic (Dominant negative, Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(ACTB-UPF1*R844C)581Hcd expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human UPF1 (5976) Upf1  (MGI:107995)   Mutation details: The human beta actin (ACTB) promoter drives expression of a dominant negative R844C mutant cDNA of the human UPF1 regulator of nonsense transcripts homolog (yeast) (UPF1) gene. Line 581 was generated. (J:162990)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:162990 Dietz HC, JR strain 10939. MGI Direct Data Submission. 2010;
All:	2 reference(s)