Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Fabp1-cre-GH1)1Jig
Name:	transgene insertion 1, Jeffrey I Gordon
MGI ID:	MGI:4820575
Synonyms:	Fabpl-596 to +21Cre-hGH
Transgene:	Tg(Fabp1-cre-GH1)1Jig  Location: unknown
Alliance:	Tg(Fabp1-cre-GH1)1Jig page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Fabp1-cre-GH1)1Jig expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Fabp1   Mutation details: A 1.0 kb fragment encoding cre recombinase was placed between nucleotides -596 to +21 of the rat Fabp1 and nucleotides +3 to +2150 of the human growth hormone gene (hGH; GH1). The purified fragment and injected into FVB/N oocytes. RNase protection assays in 8-week old mice demonstrated cre mRNA expression levels in small intestine (high in proximal half, lower in distal portion) and cecum (moderate) with barely detectable levels in the colon. Expression was also detected in the liver. (J:65809)

Activity:	Tissue activity of this recombinase allele
Driver:	Fabp1 (species not specified) Summary of all recombinase alleles driven by Fabp1. Comparative matrix view of recombinase activities

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:65809 Wong MH, et al., Genetic mosaic analysis based on cre recombinase and navigated laser capture microdissection. Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12601-6
All:	1 reference(s)