|
Results
|
Specimen
2A:
(close  )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 9.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
Specimen
2B:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
Specimen
2C:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 11.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
Specimen
2D:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
Specimen
2E:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 13.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
Specimen
2F:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: hair follicle |
Present |
|
2F
|
Expression in the ectoderm is initiated between E13.5 and E14.5, forming focal spots.
|
Specimen
3A:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Present |
Regionally restricted |
3A
|
Expression restricted to dorsal domain of optic cup.
|
Specimen
3B:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 11.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
Specimen
3C,C':
embryonic day 13.5; Bmp4tm5.1Bhr/Bmp4 +
(more  )
Specimen
3C,C':
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 13.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS21: lung epithelium |
Present |
Regionally restricted |
3C'
,
3C
|
Expression specifically elevated in the epithelium cells at the tip of lung buds.
|
Specimen
3D,D':
embryonic day 13.5; Bmp4tm5.1Bhr/Bmp4 +
(more )
Specimen
3D,D':
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 13.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS21: outflow tract |
Present |
Regionally restricted |
3D
,
3D'
|
Authors state that expression highlights the outflow tract.
|
Specimen
4A,D:
embryonic day 14.5; Bmp4tm5.1Bhr/Bmp4 +
(more )
Specimen
4A,D:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: skin |
Present |
Regionally restricted |
4D
,
4A
|
Expression first observed as evenly distributed focal spots.
|
Specimen
4B,E:
embryonic day 15.5; Bmp4tm5.1Bhr/Bmp4 +
(more )
Specimen
4B,E:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: skin |
Present |
Regionally restricted |
4B
,
4E
|
Expression outlines evenly-spaced oval-shaped structures (rings), surrounded by small brighter spots positioned asymmetrically.
|
Specimen
4C,F:
embryonic day 16.5; Bmp4tm5.1Bhr/Bmp4 +
(more )
Specimen
4C,F:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 16.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS24: skin |
Present |
Regionally restricted |
4F
,
4C
|
Expression in more rings and spots, with bigger rings further away from the spots in more mature follicles.
|
Specimen
5A:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
optical section
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: skin |
Present |
Regionally restricted |
5A
|
Expression in an aggregate of cells; stronger expression in cells in the center of focal spot.
|
Specimen
5B:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
optical section
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: skin |
Present |
Regionally restricted |
5B
|
Expression in ring of cells, with central region of non-expressing cells, and a group of strongly expression cells on one side of ring.
|
Specimen
5C,C':
embryonic day 15.5; Bmp4tm5.1Bhr/Bmp4 +
(more )
Specimen
5C,C':
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
optical section
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: skin |
Present |
Regionally restricted |
5C
,
5C'
|
Group of strongly expressing cells is olcated beneath the ring of expressing cells.
|
Specimen
5D,D':
embryonic day 16.5; Bmp4tm5.1Bhr/Bmp4 +
(more )
Specimen
5D,D':
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 16.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
optical section
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS24: skin |
Present |
Regionally restricted |
5D'
,
5D
|
Strong expression in spot, appears to move further away from ring.
|
Specimen
6A:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: hair follicle |
Present |
Regionally restricted |
6A (CFP)
|
In early stage hair placodes, expression in mesenchymal later subjacent to hair placode.
|
Specimen
6B:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 16.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS24: hair follicle |
Present |
Regionally restricted |
6B (CFP)
|
In more mature hair follicles, expression in dermal papilla of involuted hair follicles.
|
Specimen
6C:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
|
|
Mutant Allele(s):
|
Bmp4tm5.1Bhr/Bmp4+
|
|
Age:
|
embryonic day 18.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: hair follicle |
Weak |
Regionally restricted |
6C (CFP)
|
In late stage hair follicles, weaker expression in dermal papillae cells surrounded by non-expressing cells in the bulb.
|
| TS26: hair bulb |
Absent |
|
6C (CFP)
|
In late stage hair follicles, weaker expression in dermal papillae cells surrounded by non-expressing cells in the bulb.
|
|
Analysis Tools
