Tg(SFTPC-TGFA)28Kor
Transgene Detail
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Symbol: |
Tg(SFTPC-TGFA)28Kor |
Name: |
transgene insertion 28, Thomas R Korfhagen |
MGI ID: |
MGI:4819387 |
Transgene: |
Tg(SFTPC-TGFA)28Kor Location: unknown
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Alliance: |
Tg(SFTPC-TGFA)28Kor page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(SFTPC-TGFA)28Kor expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
TGFA (7039) |
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Mutation details: The entire coding region of human TGFA was fused to the human SFTPC promoter and used for the transgene. Introns from the human growth factor gene were included to enhance transgene expression. The transgene is expressed in lung epithelial cells. Lines 2, 4, 28, and 6108 were generated with 3.1-, 2.3-, 4.3-, and 1.3-fold expression, respectively.
(J:133163)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:133163 Hardie WD, et al., Dose-related protection from nickel-induced lung injury in transgenic mice expressing human transforming growth factor-alpha. Am J Respir Cell Mol Biol. 2002 Apr;26(4):430-7 |
All: |
2 reference(s) |
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