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Tg(Pdpn,-EGFP)16Dobb
Transgene Detail
Summary
Symbol: Tg(Pdpn,-EGFP)16Dobb
Name: transgene insertion 16, Leland Dobbs
MGI ID: MGI:4818480
Synonyms: RTIbacGFP, Tg(Pdpn,-EGFP)#Jnv
Transgene: Tg(Pdpn,-EGFP)16Dobb  Location: unknown  
Alliance: Tg(Pdpn,-EGFP)16Dobb page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsRTIbac clone 240G15 contains an insert of 168 kb inserted in the pBeloBAC11 vector. The sequence corresponds to nucleotides 162144322 to 162282008 of rat chromosome 5 and contains the rat podoplanin gene. An IRES-GFP sequence was placed in the 3'UTR. The resulting transgene directs expression of both rat podoplanin and GFP. Two stable founders were identified showing similar expression levels. One line was used for further study. (J:152132)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:152132 Vanderbilt JN, et al., Directed expression of transgenes to alveolar type I cells in the mouse. Am J Respir Cell Mol Biol. 2008 Sep;39(3):253-62
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory