Tg(HBB-TNF)#Xen
Transgene Detail
|
|
| Symbol: |
Tg(HBB-TNF)#Xen |
| Name: |
transgene insertion, Taconic Biosciences |
| MGI ID: |
MGI:4818272 |
| Synonyms: |
1006-T, hTNFalpha transgenic, Tg(HBB-TNF)#Tac, Tg(TNF), Tg(TNF)#Xen |
| Transgene: |
Tg(HBB-TNF)#Xen Location: unknown
|
| Alliance: |
Tg(HBB-TNF)#Xen page
|
|
| Strain of Origin: |
(C57BL/6 x SJL)
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(HBB-TNF)#Xen expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
TNF (7124) |
|
|
|
| |
|
Mutation details: The 3' UTR and flanking sequences of the human beta globin replaced the 3' region of the human TNF gene. This results in low level expression of TNF in multiple tissues not following the normal expression pattern of TNF.
(J:92576, J:162149)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:162149 Hayward MD, et al., An extensive phenotypic characterization of the hTNFalpha transgenic mice. BMC Physiol. 2007;7:13 |
| All: |
14 reference(s) |
|
Analysis Tools
