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Tg(tetO-CDK5R1*)1Vln
Transgene Detail
Summary
Symbol: Tg(tetO-CDK5R1*)1Vln
Name: transgene insertion 1, Fred Van Leuven
MGI ID: MGI:4462820
Synonyms: pBI.p25
Transgene: Tg(tetO-CDK5R1*)1Vln  Location: unknown  
Alliance: Tg(tetO-CDK5R1*)1Vln page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Tg(tetO-CDK5R1*)1Vln expresses 1 gene
 
Mutation detailsThe transgene was designed with an N-terminal truncated form of human cyclin-dependent kinase 5, regulatory subunit 1 (CDK5R1 or p35) cDNA sequence, also referred to as p25, under the control of a tetracycline operator (tetO; also called tetracycline-responsive element (TRE, TetRE) or tet-operator). (J:131373)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:131373 Muyllaert D, et al., Neurodegeneration and neuroinflammation in cdk5/p25-inducible mice: a model for hippocampal sclerosis and neocortical degeneration. Am J Pathol. 2008 Feb;172(2):470-85
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory