Tg(tetO-CDK5R1*)1Vln
Transgene Detail
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| Symbol: |
Tg(tetO-CDK5R1*)1Vln |
| Name: |
transgene insertion 1, Fred Van Leuven |
| MGI ID: |
MGI:4462820 |
| Synonyms: |
pBI.p25 |
| Transgene: |
Tg(tetO-CDK5R1*)1Vln Location: unknown
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| Alliance: |
Tg(tetO-CDK5R1*)1Vln page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Tg(tetO-CDK5R1*)1Vln expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
CDK5R1 (8851) |
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Mutation details: The transgene was designed with an N-terminal truncated form of human cyclin-dependent kinase 5, regulatory subunit 1 (CDK5R1 or p35) cDNA sequence, also referred to as p25, under the control of a tetracycline operator (tetO; also called tetracycline-responsive element (TRE, TetRE) or tet-operator).
(J:131373)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:131373 Muyllaert D, et al., Neurodegeneration and neuroinflammation in cdk5/p25-inducible mice: a model for hippocampal sclerosis and neocortical degeneration. Am J Pathol. 2008 Feb;172(2):470-85 |
| All: |
1 reference(s) |
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Analysis Tools
