Tg(Prnp*)ADah
Transgene Detail
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| Symbol: |
Tg(Prnp*)ADah |
| Name: |
transgene insertion A, David A Harris |
| MGI ID: |
MGI:4462004 |
| Synonyms: |
PrPdeltaCR, Tg(deltaCR) |
| Transgene: |
Tg(Prnp*)ADah Location: unknown
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| Alliance: |
Tg(Prnp*)ADah page
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| Strain of Origin: |
(C57BL/6J x CBA/J)F2
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion of gene trap vector
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Tg(Prnp*)ADah expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Prnp (MGI:97769) |
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Mutation details: A cDNA encoding murine Prnp with an internal deletion of sequences encoding residues 105-125 was placed under the control of a construct containing a Prnp promoter with an expression pattern similar to that of endogenous PrP, with the exception that there is no expression in cerebellar Purkinje cells. Lines B and E were also created.
(J:117788)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:117788 Li A, et al., Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125. EMBO J. 2007 Jan 24;26(2):548-58 |
| All: |
2 reference(s) |
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Analysis Tools
