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Gene Expression Data
Assay Details
Assay
Reference: J:103820 Reiter JF, et al., Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition. Genes Dev. 2006 Jan 1;20(1):22-7
Assay type: RNA in situ
MGI Accession ID: MGI:4461955
Gene symbol: Dbx1
Gene name: developing brain homeobox 1
Results
Specimen 2D left: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 2D left Expression was detected in V0 interneuron precursors.
Specimen 2D right: embryonic day 10.5; Tctn1Gt(KST296)Byg/Tctn1Gt(KST296)Byg (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 2D right Expression was detected in V0 interneuron precursors as in wild type.
Specimen 4B wild type: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 4B wild type Expression was detected in p0 precursors.
Specimen 4B Shh-/-: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: neural tube Trace Single cells 4B Shh-/- Expression is reduced to a very few cells at the ventral midline.
Specimen 4B Tectonic-/- Shh-/-: embryonic day 10.5; Tctn1Gt(KST296)Byg/Tctn1Gt(KST296)Byg, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: neural tube Present 4B Tectonic-/- Shh-/- Expression was increased in the Tcnt1/Shh double mutant compared to the Shh single mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory