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Mkxtm1.1Asah
Targeted Allele Detail
Summary
Symbol: Mkxtm1.1Asah
Name: mohawk homeobox; targeted mutation 1.1, Hiroshi Asahara
MGI ID: MGI:4461224
Gene: Mkx  Location: Chr18:6934966-7004779 bp, - strand  Genetic Position: Chr18, 4.53 cM
Alliance: Mkxtm1.1Asah page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161299
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding region of exon 2 was replaced with a Venus reporter and a floxed neo cassette. Cre mediated recombination removed the neo cassette. (J:161299)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mkx Mutation:  27 strains or lines available
References
Original:  J:161299 Ito Y, et al., The Mohawk homeobox gene is a critical regulator of tendon differentiation. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10538-42
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory