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Gene Expression Data
Assay Details
Assay
Reference: J:24142 Lutcke A, et al., Rab17, a novel small GTPase, is specific for epithelial cells and is induced during cell polarization. J Cell Biol. 1993 May;121(3):553-64
Assay type: RNA in situ
MGI Accession ID: MGI:4460816
Gene symbol: Rab17
Gene name: RAB17, member RAS oncogene family
Probe: Rab17 cDNA2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 5A, 5B: embryonic day 13.5 (more )
Note: Fig. 5A, brightfield; 5B, brightfield/darkfield illumination.
Structure Level Pattern Image Note
TS21: metanephros Absent 5B , 5A
TS21: mesenchyme of metanephros Absent 5B , 5A The undifferentiated mesenchyme and mesenchymal condensates were not labeled.
TS21: renal tubule Absent 5A , 5B The tubules at the vesicle stage were not labeled.
TS21: ureter Absent 5A , 5B The branching ureter bud in the central part and the tips of the ureter tree in the periphery were negative for expression.
Specimen 5C, 5D: embryonic day 16.5 (more )
Note: Fig. 5C, brightfield; 5D, brightfield/darkfield illumination.
Structure Level Pattern Image Note
TS24: cortical early proximal tubule Present 5D , 5C
TS24: ureteric trunk Present 5D , 5C
TS24: s-shaped body Present Regionally restricted 5C , 5D Expression was detected in the late S-shaped bodies but not in the early S-shaped bodies.
TS24: comma-shaped body Absent 5D , 5C
TS24: maturing glomerular tuft Absent 5D , 5C
TS24: ureteric tip Absent 5D , 5C
TS24: mesenchyme of metanephros Absent 5C , 5D The undifferentiated and stromal mesenchyme and early stages of tubulogenesis are unlabeled.
Specimen 5E, 5F, 5G, 5H: embryonic day 18.5 (more )
Note: Fig. 5E, brightfield; 5F, brightfield/darkfield illumination. Fig. 5G and 5H are higher magnification of boxed areas in 5E.
Structure Level Pattern Image Note
TS26: renal proximal tubule Present 5F , 5H , 5G , 5E
TS26: ureteric trunk Present 5F , 5H , 5G , 5E
TS26: s-shaped body Present Regionally restricted 5G , 5E , 5F , 5H Expression was detected in the late S-shaped bodies but not in the early S-shaped bodies.
TS26: comma-shaped body Absent 5E , 5G , 5F , 5H
TS26: glomerular tuft Absent 5E , 5G , 5F , 5H
TS26: ureteric tip Absent 5E , 5G , 5F , 5H
TS26: mesenchyme of metanephros Absent 5E , 5G , 5F , 5H The undifferentiated and stromal mesenchyme and early stages of tubulogenesis are unlabeled.
Specimen 6A, 6B: embryonic day 18.5 (more )
Note: Fig. 6A, brightfield; 6B, brightfield/darkfield illumination.
Structure Level Pattern Image Note
TS26: small intestine Present Regionally restricted 6B , 6A Expression was confined to the columnar epithelium covering the plicae and villi projecting into the intestinal lumen. No expression was detected in the sub-epithelial mesenchymal part of these projections.
Specimen 6C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: small intestine Present Regionally restricted 6C Expression was strong in the intestinal epithelium, but absent from the nonepithelial tissues of the Tunica Submucosa, Tunica Muscularis and Tunica Serosa.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory