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Gene Expression Data
Assay Details
Assay
Reference: J:160025 Rantakari P, et al., Hydroxysteroid (17{beta}) dehydrogenase 12 is essential for mouse organogenesis and embryonic survival. Endocrinology. 2010 Apr;151(4):1893-901
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:4460701
Gene symbol: Hsd17b12
Gene name: hydroxysteroid (17-beta) dehydrogenase 12
Reporter: lacZ
Direct Detection
Assay notes: Fixative was 0.2% glutaraldehyde, post-stained embryos were further fixed in 4%paraformaldehyde.
Results
Specimen 2B: embryonic day 7.5; Hsd17b12Gt(A030E06)Wrst/Hsd17b12+ (more )
Structure Level Pattern Image Note
TS11: embryo ectoderm Weak 2B

Specimen 2C: embryonic day 7.5; Hsd17b12Gt(A030E06)Wrst/Hsd17b12+ (more )
Structure Level Pattern Image Note
TS11: embryo ectoderm Weak 2C

Specimen 2D: embryonic day 8.5; Hsd17b12Gt(A030E06)Wrst/Hsd17b12+ (more )
Structure Level Pattern Image Note
TS13: future hindbrain neural fold Strong 2D
TS13: future midbrain neural fold Strong 2D
TS13: future prosencephalon neural fold Strong 2D
TS13: future spinal cord neural fold Strong 2D

Specimen 2E: embryonic day 8.5; Hsd17b12Gt(A030E06)Wrst/Hsd17b12+ (more )
Structure Level Pattern Image Note
TS13: future hindbrain neural fold Strong 2E
TS13: future midbrain neural fold Strong 2E
TS13: future prosencephalon neural fold Strong 2E
TS13: future spinal cord neural fold Strong 2E

Specimen 2F: embryonic day 8.5; Hsd17b12Gt(A030E06)Wrst/Hsd17b12+ (more )
Structure Level Pattern Image Note
TS13: neural fold Strong 2F
TS13: neural tube Strong 2F

Specimen 2G: embryonic day 9.5; Hsd17b12Gt(A030E06)Wrst/Hsd17b12+ (more )
Structure Level Pattern Image Note
TS15: embryo Present Widespread 2G
TS15: neural tube Strong Regionally restricted 2G Expression is dorsal.

Specimen 2H: embryonic day 9.5; Hsd17b12Gt(A030E06)Wrst/Hsd17b12+ (more )
Structure Level Pattern Image Note
TS15: embryo Present Widespread 2H
TS15: heart Present 2H

Specimen 2I: embryonic day 9.5; Hsd17b12Gt(A030E06)Wrst/Hsd17b12+ (more )
Structure Level Pattern Image Note
TS15: embryo Present Widespread 2I
TS15: neural tube Strong Regionally restricted 2I Expression is dorsal.

Specimen 2J: embryonic day 9.5; Hsd17b12Gt(A030E06)Wrst/Hsd17b12+ (more )
Structure Level Pattern Image Note
TS15: embryo Present Widespread 2J
TS15: neural tube Strong Regionally restricted 2J Expression is dorsal.
TS15: otocyst Strong 2J

Specimen Not shown E7.5: embryonic day 7.5; Hsd17b12Gt(A030E06)Wrst/Hsd17b12+ (more )
Structure Level Pattern Image Note
TS11: yolk sac Present

Specimen Not shown E8.5: embryonic day 8.5; Hsd17b12Gt(A030E06)Wrst/Hsd17b12+ (more )
Structure Level Pattern Image Note
TS13: ectoplacental cone Present
TS13: yolk sac Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory