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Gene Expression Data
Assay Details
Assay
Reference: J:158405 Liang L, et al., Insulin-like growth factor 2 and the insulin receptor, but not insulin, regulate fetal hepatic glycogen synthesis. Endocrinology. 2010 Feb;151(2):741-7
Assay type: RT-PCR
MGI Accession ID: MGI:4457414
Gene symbol: Insr
Gene name: insulin receptor
Results Image: 2
 Sample Information Bands Other Sample Information
Lane AgeStructure 254 bp (b) 218 bp (d) Amount Genetic BackgroundMutant Allele(s)Sex
e13 Igf2+/+ E13.5 (a) TS21: liver Present (c) Present (e) Not Specified; total RNA involves: 129S/SvEv Not Specified
e13 Igf2-/- E13.5 (a) TS21: liver Present (f) Present (f) Not Specified; total RNA involves: 129S/SvEv Igf2tm1Rob/Igf2tm1RobNot Specified
e15 Igf2+/+ E15.5 (a) TS23: liver Present (g) Present (g) Not Specified; total RNA involves: 129S/SvEv Not Specified
e15 Igf2-/- E15.5 (a) TS23: liver Present (f) Present (f) Not Specified; total RNA involves: 129S/SvEv Igf2tm1Rob/Igf2tm1RobNot Specified
e18 Igf2+/+ E18.5 (a) TS26: liver Present (c) Present (e) Not Specified; total RNA involves: 129S/SvEv Not Specified
e18 Igf2-/- E18.5 (a) TS26: liver Present (f) Present (f) Not Specified; total RNA involves: 129S/SvEv Igf2tm1Rob/Igf2tm1RobNot Specified
Adult Igf2+/+ P adult TS28: liver Present (c) Present (e) Not Specified; total RNA involves: 129S/SvEv Not Specified
Adult Igf2-/- P adult TS28: liver Present (f) Present (f) Not Specified; total RNA involves: 129S/SvEv Igf2tm1Rob/Igf2tm1RobNot Specified
Notes:
(a) Age normalized so that noon of plug day = E0.5.
(b) This represents the IR-B isoform.
(c) This is the major isoform.
(d) This represents the IR-A isoform.
(e) IR-A expression were significantly higher in the fetal liver than in the adult.
(f) Expression of this isoform in this mutant is the same as in wild-type.
(g) Both isoforms have nearly identical levels.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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