Bloc1s2tm1(KOMP)Mbp
Targeted Allele Detail
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Symbol: |
Bloc1s2tm1(KOMP)Mbp |
Name: |
biogenesis of lysosomal organelles complex-1, subunit 2; targeted mutation 1, Mouse Biology Program, UC Davis |
MGI ID: |
MGI:4456579 |
Gene: |
Bloc1s2 Location: Chr19:44127685-44134885 bp, - strand Genetic Position: Chr19, 36.72 cM, cytoband D1
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Alliance: |
Bloc1s2tm1(KOMP)Mbp page
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IMPC: |
Bloc1s2 gene page |
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Mutant Cell Lines: |
DEPD00501_4_A09, DEPD00501_4_A12, DEPD00501_4_B11, DEPD00501_4_C09, DEPD00501_4_C10, DEPD00501_4_C11, DEPD00501_4_D09, DEPD00501_4_D12, DEPD00501_4_E09, DEPD00501_4_E10, DEPD00501_4_E12, DEPD00501_4_F09, DEPD00501_4_G09, DEPD00501_4_G10, DEPD00501_4_G11, DEPD00501_4_G12, DEPD00501_4_H09, DEPD00501_4_H12 |
Germline Transmission: |
Earliest citation of germline transmission:
J:188991
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Parent Cell Line: |
JM8A3 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 3986 starting at position 44130535 and ending at position 44134521 of Chromosome 19 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157064)
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Original: |
J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010; |
All: |
2 reference(s) |
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