Tg(ACTB-BDNF)#Gdy
Transgene Detail
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| Symbol: |
Tg(ACTB-BDNF)#Gdy |
| Name: |
transgene insertion, George Yancopoulos |
| MGI ID: |
MGI:4456441 |
| Transgene: |
Tg(ACTB-BDNF)#Gdy Location: unknown
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| Alliance: |
Tg(ACTB-BDNF)#Gdy page
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| Strain of Origin: |
(CBA x C57BL/6)F2
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(ACTB-BDNF)#Gdy expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
BDNF (627) |
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Mutation details: A human beta Actin promoter was used to drive expression of a human BDNF cDNA. Two founders carried two copies at a single integration site. Both lines were very similar so only one was maintained. Expression dropped between 8 weeks and 9 months of age.
(J:59465)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:59465 Croll SD, et al., Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex. Neuroscience. 1999;93(4):1491-506 |
| All: |
2 reference(s) |
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Analysis Tools
