Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Atoh1tm1(cre)Gan
Name:	atonal bHLH transcription factor 1; targeted mutation 1, Lin Gan
MGI ID:	MGI:4455013
Synonyms:	Atoh1cre
Gene:	Atoh1  Location: Chr6:64706109-64708229 bp, + strand  Genetic Position: Chr6, 30.03 cM
Alliance:	Atoh1tm1(cre)Gan page

Germline Transmission:	Earliest citation of germline transmission: J:160667
Parent Cell Line:	W4 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Recombinase) Mutations:    Insertion, Intragenic deletion   Atoh1tm1(cre)Gan expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Atoh1 (MGI:104654)   Mutation details: A targeting construct was used to replace the complete coding sequence of Atoh1 with the cre recombinase sequence so that cre expression was controlled by the Atoh1 regulatory sequences. The knockin allele was generated in W4 ES cells. (J:160667)

Generation of the Atoh1tm1(cre)Gan allele

Activity:	Tissue activity of this recombinase allele
Driver:	Atoh1 (mouse) Summary of all recombinase alleles driven by Atoh1. Comparative matrix view of recombinase activities Alliance mouse Atoh1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

20 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atoh1 Mutation:	36 strains or lines available

Original:	J:160667 Yang H, et al., Generation and characterization of Atoh1-Cre knock-in mouse line. Genesis. 2010 Apr 13;48(6):407-413
All:	33 reference(s)