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Gene Expression Data
Assay Details
Assay
Reference: J:81365 Murdoch JN, et al., Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse. Hum Mol Genet. 2003 Jan 15;12(2):87-98
Assay type: RNA in situ
MGI Accession ID: MGI:4453633
Gene symbol: Scrib
Gene name: scribbled planar cell polarity
Probe: Scrb1 cDNA
Probe preparation: Antisense RNA
Results
Specimen Not shown: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Present
Specimen 3B, C: embryonic day 8.5 (more )
Note: B, lateral and C, dorsal views
Structure Level Pattern Image Note
TS13: embryo Present Regionally restricted 3B , 3C Expression extends in a longitudinal domain along the length of the embryo.
Specimen 3D: embryonic day 8.5 (more )
Note: (D-G) Transverse sections through the embryo shown in (B).
Structure Level Pattern Image Note
TS13: neural ectoderm Strong 3D
TS13: head mesenchyme Present 3D
Specimen 3E: embryonic day 8.5 (more )
Note: (D-G) Transverse sections through the embryo shown in (B).
Structure Level Pattern Image Note
TS13: branchial arch Present 3E
Specimen 3F: embryonic day 8.5 (more )
Note: (D-G) Transverse sections through the embryo shown in (B).
Structure Level Pattern Image Note
TS13: somite Weak 3F
TS13: trunk unsegmented mesenchyme Weak 3F
Specimen 3G: embryonic day 8.5 (more )
Note: (D-G) Transverse sections through the embryo shown in (B).
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Weak 3G
TS13: somite Weak 3G
TS13: trunk unsegmented mesenchyme Weak 3G
Specimen 3I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch Present 3I
TS17: heart Present 3I
TS17: neural tube Present 3I
TS17: trachea Present 3I
Specimen 3J: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 3J
TS17: hepatic primordium Present 3J
TS17: limb Present 3J
TS17: midgut epithelium Present 3J
TS17: neural tube Present 3J
TS17: body wall mesenchyme Present Regionally restricted 3J Expression is in the medial body wall.
Specimen 3K: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: retina Very strong 3K
Specimen 3L: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: retina Very strong 3L
TS23: eyelid epithelium Very strong 3L Particularly at the region of eyelid fusion.
Specimen 3M: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hair follicle Present 3M
TS23: vibrissa follicle Present 3M
Specimen 3N: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hair follicle Present 3N
TS23: vibrissa follicle Present 3N
Specimen 3O: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: submandibular gland primordium Present 3O
Specimen 3P: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: dorsal root ganglion Present 3P
TS23: esophagus Present 3P
TS23: sympathetic ganglion Present 3P
TS23: thymus primordium Present 3P
TS23: trachea Present 3P
Specimen 3Q: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: stomach epithelium Present 3Q
TS22: testis Present 3Q
Specimen 3R: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlea Present 3R
TS22: trigeminal ganglion Present 3R
Specimen 3S: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: metanephros Present 3S
Specimen 3T: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung epithelium Present 3T
Specimen 5E: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: floor plate Trace 5E Expression appears to be reduced or absent from the developing floor plate.
Specimen 5F: embryonic day 9.0; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS14: floor plate Trace 5F Expression in this mutant is the same as in wild-type embryos.
Specimen 5G: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: floor plate Trace 5G Expression appears to be reduced or absent from the developing floor plate.
Specimen 5H: embryonic day 9.0; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS14: floor plate Trace 5H Expression in this mutant is in a larger area compared to wild-type.
Specimen 5I: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: floor plate Trace 5I Expression appears to be reduced or absent from the developing floor plate.
Specimen 5J: embryonic day 9.0; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS14: floor plate Trace 5J Expression in this mutant is the same as in wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory