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Osr2tm1Pzg
Targeted Allele Detail
Summary
Symbol: Osr2tm1Pzg
Name: odd-skipped related 2; targeted mutation 1, Pumin Zhang
MGI ID: MGI:4441462
Synonyms: Osr2RFP, Osr2-RFP, Osr2tm1Zhang
Gene: Osr2  Location: Chr15:35296244-35303451 bp, + strand  Genetic Position: Chr15, 14.46 cM
Alliance: Osr2tm1Pzg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:159099
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting vector containing the Red Fluorescent Protein (RFP) gene followed, in reverse orientation, by two copies of a loxP and frt site-flanked kanamycin and neomycin resistance cassette (loxP-pA-frt-Kan&Neo-frt-loxP) was inserted into the first coding exon of the endogenous gene immediately following the ATG translation initiation codon. Strong red fluorescence is detected the head, testes and male and female genital ducts and kidneys from heterozygous E15.5 embryos, mimicking the expression pattern of the endogenous gene. (J:159099)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Osr2 Mutation:  17 strains or lines available
References
Original:  J:159099 McMahon A, et al., Summary of mouse strains characterized by GUDMAP consortium. Unpublished. 2010;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory