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Id3tm1Pzg
Targeted Allele Detail
Summary
Symbol: Id3tm1Pzg
Name: inhibitor of DNA binding 3; targeted mutation 1, Pumin Zhang
MGI ID: MGI:4441450
Synonyms: Id3-RFP, Id3tm1Zhang
Gene: Id3  Location: Chr4:135871133-135872703 bp, + strand  Genetic Position: Chr4, 68.34 cM
Alliance: Id3tm1Pzg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:159099
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting vector containing the Red Fluorescent Protein (RFP) gene followed, in reverse orientation, by two copies of a loxP and frt site-flanked kanamycin and neomycin resistance cassette (loxP-pA-frt-Kan&Neo-frt-loxP) was inserted into the first coding exon of the endogenous gene immediately following the ATG translation initiation codon. Mice with this mutation exhibit a strong red fluorescent signal in the kidney, and E15.5 heterozygous mutant embryos exhibit fluorescence in the urogenital system that mimics the expression pattern of the endogenous gene. (J:159099)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Id3 Mutation:  16 strains or lines available
References
Original:  J:159099 McMahon A, et al., Summary of mouse strains characterized by GUDMAP consortium. Unpublished. 2010;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory