About   Help   FAQ
Intutm1.2Aliu
Targeted Allele Detail
Summary
Symbol: Intutm1.2Aliu
Name: inturned planar cell polarity protein; targeted mutation 1.2, Aimin Liu
MGI ID: MGI:4441401
Synonyms: IntudeltaEx2
Gene: Intu  Location: Chr3:40585559-40659206 bp, + strand  Genetic Position: Chr3, 19.46 cM
Alliance: Intutm1.2Aliu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:159120
Parent Cell Line:  BK4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed exon 2. The absence of protein expression was confirmed by western blot analysis on E10.5 embryo extracts. (J:159120)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 84 assay results
In Structures Affected by this Mutation: 13 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Intu Mutation:  45 strains or lines available
References
Original:  J:159120 Zeng H, et al., PCP effector gene Inturned is an important regulator of cilia formation and embryonic development in mammals. Dev Biol. 2010 Mar 15;339(2):418-28
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory