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Gene Expression Data
Assay Details
Assay
Reference: J:21058 Yamada S, et al., Integrin regulatory switching in development: oscillation of beta 5 integrin mRNA expression during epithelial-mesenchymal interactions in tooth development. Int J Dev Biol. 1994 Sep;38(3):553-6
Assay type: RNA in situ
MGI Accession ID: MGI:4441073
Gene symbol: Itgb5
Gene name: integrin beta 5
Probe: MB5.AC
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Probes were reduced to approximately 150 bases by limited alkaline hydrolysis.
Results
Specimen 1B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lower jaw Present 1B
TS21: upper jaw Present 1B
Specimen 2A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: maxillary process epithelium Present Regionally restricted 2A Diffuse expression in epithelial of the first molar. Expression was higher in the epithelium.
TS20: maxillary process mesenchyme Present Regionally restricted 2A Diffuse expression in dental mesenchyme of the first molar. Expression was higher in the epithelium.
Specimen 2B: embryonic day 13.5 (more )
Note: Bud stage of tooth development.
Structure Level Pattern Image Note
TS21: upper jaw molar mesenchyme Present 2B
TS21: upper jaw molar epithelium Weak 2B
Specimen 2C: embryonic day 14.5 (more )
Note: Cap stage of tooth development.
Structure Level Pattern Image Note
TS22: upper jaw molar enamel organ Very strong Regionally restricted 2C Expression is in the enamel epithelium, especially on the lingual side, low in mesenchymal cells and epithelial cells of the stellate reticulum and outer enamel epithelium of the first molar.
TS22: outer enamel epithelium Weak 2C
TS22: stellate reticulum Weak 2C
TS22: upper jaw molar mesenchyme Weak 2C
TS22: enamel epithelium Very strong 2C Especially on the lingual side.
Specimen 2D: embryonic day 15.5 (more )
Note: Early bell stage of tooth development.
Structure Level Pattern Image Note
TS23: inner enamel epithelium Present Regionally restricted 2D Expression is in the inner enamel epithelium of the first molar.
TS23: upper jaw molar enamel organ Present Regionally restricted 2D Expression is in the inner enamel epithelium of the first molar.
Specimen Not shown, E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar enamel organ Very strong Regionally restricted Expression is in the enamel epithelium, especially on the lingual side, low in mesenchymal cells and epithelial cells of the stellate reticulum and outer enamel epithelium.
TS22: lower jaw molar mesenchyme Weak
TS22: outer enamel epithelium Weak
TS22: stellate reticulum Weak
TS22: enamel epithelium Very strong Regionally restricted Especially on the lingual side.
Specimen Not shown, E18.5: embryonic day 18.5 (more )
Note: Late bell stage of tooth development.
Structure Level Pattern Image Note
TS26: inner enamel epithelium Present Regionally restricted Expression is in the inner enamel epithelium of the first molar.
TS26: upper jaw molar enamel organ Present Regionally restricted Expression is in the inner enamel epithelium of the first molar.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory