Tg(H2-Ea-Cd74/MCC*K99E)10GNnak
Transgene Detail
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| Symbol: |
Tg(H2-Ea-Cd74/MCC*K99E)10GNnak |
| Name: |
transgene insertion 10G, Naoko Nakano |
| MGI ID: |
MGI:4439129 |
| Synonyms: |
Ii-99E |
| Transgene: |
Tg(H2-Ea-Cd74/MCC*K99E)10GNnak Location: unknown
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| Alliance: |
Tg(H2-Ea-Cd74/MCC*K99E)10GNnak page
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| Strain of Origin: |
(C57BL/6 x SJL)F2
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(H2-Ea-Cd74/MCC*K99E)10GNnak expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Cd74 (MGI:96534) |
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Mutation details: The H2-Ea promoter was used to control expression of a fusion protein composed of Cd74 (MHC II invarient chain) and sequence encoding amino acid residues 88-103 of moth cytochrome c. A mutation was created in the codon for amino acid residue 99 resulting in a lysine to glutamic acid substitution.
(J:133061)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:133061 Yamashiro H, et al., Development of CD25(+) T cells secreting transforming growth factor-beta1 by altered peptide ligands expressed as self-antigens. Int Immunol. 2002 Aug;14(8):857-65 |
| All: |
1 reference(s) |
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Analysis Tools
