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Gene Expression Data
Assay Details
Assay
Reference: J:157563 Snyder-Warwick AK, et al., Analysis of a gain-of-function FGFR2 Crouzon mutation provides evidence of loss of function activity in the etiology of cleft palate. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2515-20
Assay type: RNA in situ
MGI Accession ID: MGI:4438195
Gene symbol: Fgfr2
Gene name: fibroblast growth factor receptor 2
Probe: Fgfr2-TK probe
Probe preparation: Antisense labelled with P32 RNA
Assay notes: Authors do not specify probe used; FGFR2IIIb cDNA2 (MGI:2159018) may also have been used. Specimens were fixed with either 10% formalin or 4% paraformaldehyde.
Results
Specimen 1A': embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf Weak Regionally restricted 1A' Little expression in the soft palate.
Specimen 1B': embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf Strong Regionally restricted 1B' Strongest expression in the posterior hard palate in palatal shelf mesenchyme, with strong focal expression on the superior nasal half of the shelf.
Specimen 1C': embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf Weak Regionally restricted 1C' Little expression in the middle hard palate.
Specimen 1D': embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf Weak Regionally restricted 1D' Little expression in the anterior hard palate.
Specimen S1A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf Weak Regionally restricted S1A Little expression in the anterior region of the palate.
Specimen S1B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Strong Regionally restricted S1B Strongest expression in the posterior palatal shelf mesenchyme, with strong focal expression on the superior nasal half of the shelf.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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