Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hapln2tm1Ooh
Name:	hyaluronan and proteoglycan link protein 2; targeted mutation 1, Toshitaka Oohashi
MGI ID:	MGI:4437572
Synonyms:	Bral1-
Gene:	Hapln2  Location: Chr3:87929057-87934890 bp, - strand  Genetic Position: Chr3, 38.78 cM, cytoband F1
Alliance:	Hapln2tm1Ooh page

Germline Transmission:	Earliest citation of germline transmission: J:157824
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A lacZ neo cassette was inserted within exon 4 by homologous recombination. Northern blot analysis of polyA+ RNA isolated from the brain showed absence of transcript. Western blotting demonstrated the complete absence of the full length protein. (J:157824)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hapln2 Mutation:	19 strains or lines available

Original:	J:157824 Bekku Y, et al., Bral1: its role in diffusion barrier formation and conduction velocity in the CNS. J Neurosci. 2010 Feb 24;30(8):3113-23
All:	2 reference(s)