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Gene Expression Data
Assay Details
Assay
Reference: J:156193 Etokebe GE, et al., Family-with-sequence-similarity-46, member A (Fam46a) gene is expressed in developing tooth buds. Arch Oral Biol. 2009 Nov;54(11):1002-7
Assay type: RNA in situ
MGI Accession ID: MGI:4437467
Gene symbol: Tent5a
Gene name: terminal nucleotidyltransferase 5A
Probe: pFAM46A.7
Probe preparation: Antisense labelled with digoxigenin RNA
Assay notes: These specimens were processed independently, and thus, hybridisation intensities are not comparable.
Results
Specimen 2A: embryonic day 12.5 (more )
Note: This is a late dental lamina/early bud stage tooth bud.
Structure Level Pattern Image Note
TS20: oral region Present Regionally restricted 2A There is widespread expression in the dental sheet, oral epithelium, mesenchyme, and in cells surrounding the tooth bud.
Specimen 2B: embryonic day 13.5 (more )
Note: This is a bud stage tooth bud.
Structure Level Pattern Image Note
TS21: tooth Present 2B Expression is present in the tooth germ bud, including the ectomesenchyme.
TS21: oral epithelium Present 2B
Specimen 2C: embryonic day 14.5 (more )
Note: This is an early cap stage molar.
Structure Level Pattern Image Note
TS22: molar dental papilla Present 2C Expression is pronounced.
TS22: molar epithelium Present 2C Expression is pronounced.
Specimen 2D: embryonic day 16.5 (more )
Note: This is a late cap/early bell stage molar.
Structure Level Pattern Image Note
TS24: molar dental papilla Present 2D
TS24: molar epithelium Present 2D
Specimen 2E: embryonic day 17.5 (more )
Note: This is a late bell stage molar.
Structure Level Pattern Image Note
TS25: molar Present Non-Uniform 2E Expression is found predominantly in the outer epithelium. However, areas under going enamel production have stronger expression than adjacent areas with a lower generation of enamel. It is also present in the inner epithelium.
TS25: molar dental papilla Present Regionally restricted 2E Expression is present in the outer dental papilla.
Specimen 2F: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: incisor Strong Regionally restricted 2F Expression is predominantly in the ameloblast nuclei. It correlates with the strong production of enamel.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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