Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ptprttm1Sata
Name:	protein tyrosine phosphatase receptor type T; targeted mutation 1, Masanobu Satake
MGI ID:	MGI:4437410
Synonyms:	PTPRT-, Ptprttm1Zhw
Gene:	Ptprt  Location: Chr2:161363910-162503067 bp, - strand  Genetic Position: Chr2, 81.91 cM
Alliance:	Ptprttm1Sata page

Germline Transmission:	Earliest citation of germline transmission: J:157542
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 22, containing the phosphatase catalytic core motif of the first catalytic domain, was replaced with a PGK-NeobpA cassette. (J:157542)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptprt Mutation:	87 strains or lines available

Original:	J:157542 Zhao Y, et al., Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2592-7
All:	3 reference(s)