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Tg(tetO-NOTCH1*)1Rwng
Transgene Detail
Summary
Symbol: Tg(tetO-NOTCH1*)1Rwng
Name: transgene insertion 1, Rong Wang
MGI ID: MGI:4431200
Synonyms: TRE-Notch1ICD
Transgene: Tg(tetO-NOTCH1*)1Rwng  Location: unknown  
Alliance: Tg(tetO-NOTCH1*)1Rwng page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation details: DNA encoding amino acid residues 1756-2556 of human NOTCH1 was placed under the control of the tetracycline response element. (J:99859)
Tumor Data
List all tumor models in MMHCdb carrying Tg(tetO-NOTCH1*)1Rwng
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:99859 Carlson TR, et al., Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9884-9
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory