Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(Csf1r-icre)1Jwp
Name:	transgene insertion 1, Jeffrey W Pollard
MGI ID:	MGI:4429470
Synonyms:	cfms-icre, Csf1rMeriCreMer, Tg(Csf1.icre)jwp, Tg(Csf1r-iCre)jwp, tg(Csf1r-Meri-iCre- Mer)1Jwp
Transgene:	Tg(Csf1r-icre)1Jwp  Location: unknown
Alliance:	Tg(Csf1r-icre)1Jwp page

Strain of Origin:

FVB

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Csf1r-icre)1Jwp expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Csf1r   Mutation details: A transgenic construct was made with the icre (improved cre) sequence inserted downstream of the colony-stimulating factor-1 receptor (Csf1r) promoter. The construct was injected into FVB embryos. One of three founders transmitted the transgene to offspring and a line was established from this founder. (J:156593)

Activity:	Tissue activity of this recombinase allele
Driver:	Csf1r (species not specified) Summary of all recombinase alleles driven by Csf1r. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

3 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available

Original:	J:156593 Deng L, et al., A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis. Am J Pathol. 2010 Feb;176(2):952-67
All:	55 reference(s)